Pharmacogenomics – PGx Testing Services in Colorado

The PGx test can be useful for understanding the impact of the medications that are being used today but can also help for future treatments. This is because many commonly prescribed medications are impacted by a handful of genes so there will be overlap for results and it is highly likely that the result of one PGx test will be useful for future treatments. Because a PGx test result can help to inform other treatment decisions in the future for a patient’s care, results should be shared with other providers and potentially even the patient’s pharmacist.

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    PGX Testing Services in Colorado
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    What is Pharmacogenomics Testing (PGx)?

    Pharmacogenomics is the study of genetic variations that influence an individual’s response to medications. Each person responds uniquely to treatment so the same approach may not be effective or may cause adverse side effects in other patients. Understanding this information is helpful to physicians in developing a strategy to optimize medicine therapies. Data with respect to a patient’s genotype is used to maximize medicine efficacy while minimizing adverse drug effects and drug-drug interactions.

    In Short, Pharmacogenomic (PGx) testing saves lives, by helping physicians prescribe the right medication for a patient taking the guesswork and the trial & error out of prescribing and decreasing the time to proper treatment.

    A single test designed to inform treatment decisions:

    ✔ Patients demonstrating sensitivity or lack of symptom relief.

    ✔ Patients with chronic conditions and multiple prescriptions.

    ✔ Patients with a history of poor compliance.

    ✔ Patients with pharmacotherapy failure.

    ✔ Patients with a personal or family history of adverse medical reactions in response to certain medications.

    What is Pharmacogenomics Testing (PGx)?

    Pharmacogenomics is the study of genetic variations that influence an individual’s response to medications. Each person responds uniquely to treatment so the same approach may not be effective or may cause adverse side effects in other patients. Understanding this information is helpful to physicians in developing a strategy to optimize medicine therapies. Data with respect to a patient’s genotype is used to maximize medicine efficacy while minimizing adverse drug effects and drug-drug interactions.

    In Short, Pharmacogenomic (PGx) testing saves lives, by helping physicians prescribe the right medication for a patient taking the guesswork and the trial & error out of prescribing and decreasing the time to proper treatment.

    The PGx Test can be useful for understanding the impact of the medications that are being used today but can also help for future treatments. This is because many commonly prescribed medicine are impacted by a handful of genes so there will be overlap for results and it is highly likely that the result of one PGx test will be useful for future treatments. Because a PGx test result can help to inform other treatment decisions in the future for a patient’s care, results should be shared with other providers and potentially even the patient’s pharmacist.

    A single test designed to inform treatment decisions:

    ✔ Patients demonstrating sensitivity or lack of symptom relief.

    ✔ Patients with chronic conditions and multiple prescriptions.

    ✔ Patients with a history of poor compliance.

    ✔ Patients with pharmacotherapy failure.

    ✔ Patients with a personal or family history of adverse medical reactions in response to certain medications.

    Adverse Drug Reactions

    Adverse drug reactions are a leading cause of death nationwide. The FDA highlights pharmacogenomics data for more than 130 prescription medications indicating their strong support for testing.

    Pharmacogenomic (PGx) Testing provides evidence-based, actionable data for clinicians. This will help predict if a patient is likely to experience an adverse drug reaction or not respond to a given medicine at all.

    The level of medicine interactions is reported with warnings, level of documentation, and clinical management recommendations.

    Why does some medicine work for some people while not for others? Everyone’s metabolism is different.

    What is Pharmacogenomics Testing (PGx)?

    Pharmacogenomics is the study of genetic variations that influence an individual’s response to medications. Each person responds uniquely to treatment so the same approach may not be effective or may cause adverse side effects in other patients. Understanding this information is helpful to physicians in developing a strategy to optimize medicine therapies. Data with respect to a patient’s genotype is used to maximize medicine efficacy while minimizing adverse drug effects and drug-drug interactions.

    In Short, Pharmacogenomic (PGx) testing saves lives, by helping physicians prescribe the right medication for a patient taking the guesswork and the trial & error out of prescribing and decreasing the time to proper treatment.

    A single test designed to inform treatment decisions:

    ✔ Patients demonstrating sensitivity or lack of symptom relief.

    ✔ Patients with chronic conditions and multiple prescriptions.

    ✔ Patients with a history of poor compliance.

    ✔ Patients with pharmacotherapy failure.

    ✔ Patients with a personal or family history of adverse medical reactions in response to certain medications.

    What type of results can you expect?

    Why do drugs work for some people while not for others? Everyone’s metabolism is different.

    • Extensive (normal) Metabolizer
    • Intermediate Metabolizer
    • Poor Metabolizer
    • Ultra-rapid Metabolizer

    Based on genetics, everyone has the potential to respond to medication differently:

    • Medication is ineffective
    • Patient experiences unexpected reaction
    • Serious side effect occurs
    • A higher dosage is needed
    • A lower dosage is needed

    Why play trial and error with your 

    medication when you can know for sure?

     

    Common Medications Affected

    Results are available to you in 7-14 days. Why wait to see if a medication will work when you can know for sure?

    Common medications affected by drug/gene and drug/drug interactions where patients should be genetically tested for:

     

    Abacavir Ado-Trastuzumab Emtansine Afatinib
    Amitriptyline Anastrozole Aripiprazole
    Arsenic Trioxide Atomoxetine Azathioprine
    Boceprevir Bosutinib Busulfan
    Capecitabine Carbamazepine Carglumic Acid
    Carisoprodol Carvedilol Calecoxib
    Cetuximab Cevimeline Chloroquine
    Chlorpropamide Cisplatin Citalopram
    Clobazam Clomipramine Clopidogrel
    Clozapine Codeine Crizotinib
    Dabrafenib Dapsone Dasatinib
    Denileukin Diftitox Desipramin Dexlansoprazole
    Dextromethorphan and Quinidine Dizaepam Doxepin
    Drospirenone and Ethinyl Estradiol Eltrombopag Erlotinib
    Esomeprazole Everolimus Exemestane
    Flurouracil Fluoxetine Flurbiprofen
    Fluvoxamine Fulvestrant Galantamine
    Glimepiride Glipizide Glyburide
    Ibritumomab Tiuxetan Iloperidone Imatinib
    Imipramine Indacaterol Irinotecan
    Isosorbide and Hydralazine Ivacaftor Lansoprazole
    Lapatinib Lenalidomide Letrozole
    Lomitapide Mafenide Maraviroc
    Mercaptopurine Methylene Blue Metoclopramide
    Metoprolol Mipomersen Modafinil
    Mycophenolic Acid Nalidixic Acid Nefazodone
    Nilotinib Nitrofurantoin Nortriptyline
    Obinutuzumab Ofatumumab Omacetaxine
    Omeprazole Panitumumab Pantoprazole
    Paroxetine Pazopanib PEG-3350
    Peginterferon alfa-2b Pegloticase Perphenazine
    Petuzumab Phenytoin Pimozide
    Ponatinib Prasugrel Pravastatin
    Primaquin Propafenone Propranolol
    Protriptyline Quinidine Quinine Sulfate
    Rabeprazole Rasburicase Rifampin
    Risperidone Rituximab Rsuvastatin
    Simeprevir Sodium Nitrate Sofosbuvir
    Succimer Sulfamethoxazole Tamoxifen
    Telaprevir Terbinafine Tetrabenazine
    Thioguanine Thioridazine Ticagrelor
    Tolterodine Tositumomab Tramadol
    Trametinib Trastuzumab Tretinoin
    Trimipramine Valproic Acid Vemurafenib
    Venlafaxine Voriconazole Vortioxetine
    Warfarin

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